Do COVID-19 RNA-Injections Affect Male Fertility? Latest Facts and Perspective. New study from Germany!

Since the introduction of novel mRNA injections in the late 2020s, a large number of studies, data reviews from public databases, and anecdotal evidence and reports from doctors' offices and IVF clinics have been published on vaccine side effects as a result of mRNA injections - suggesting an enormous potential risk to healthy reproductive capacity. A comprehensive compilation of the data on pregnancy complications, as well as their plausible toxicological causes, have already been discussed in detail on our blog. We have also reported in detail on the toxicological risks of vaccine side effects on male fertility and the literature published to date.

A study with the title "Do COVID-19 RNA-Injections Affect Male Fertility? Latest Facts and Perspective." from Germany was published today, January 27, 2023.¹ and provides an overview of the data situation in clear terms.

The ^study1 entitled "Do COVID-19 RNA Injections Affect Male Fertility? Latest Facts and Perspective" from Germany provides a detailed overview of the data on vaccination side effects as a result of Covid injections on male fertility. The authors are the German molecular biologist Prof. Dr. Klaus Steger, who conducts research in the field of molecular andrology at the Biomedical Research Center of the University of Giessen, and Prof. Dr. Werner Bergholz - an expert in quality management and data analysis.

Various databases on the occurrence of male reproductive tract diseases as a result of Covid injections were analyzed, as well as previously published studies investigating the effects of Covid injections on sperm quality or the success rate of assisted reproduction treatments. A comprehensive molecular biology background analysis details the actual long-term risks posed by vaccination side effects of mRNA technology on the male reproductive tract.

"It was furthermore pointed out that the mRNA used is not, as is often claimed, "simple mRNA", but so-called `modRNA` (modified RNA), which has a completely different effect in the body..."

In summary, previously published studies on pre- & post-analysis of semen samples show massive deficiencies in the study design - especially the observed measurement periods over which vaccination side effects should be measured. Database analyses (UK Yellow Card, US VAERS as well as deStatis) show a clear association between erectile dysfunction (ED) and heart failure as well as a significant decline in fertility exactly 9 months after the start of the vaccination campaign, which may also be attributable to secondary infertility (infertility due to concomitant diseases of the reproductive tract). It was also pointed out that the mRNA used is not "simple mRNA", as is often claimed, but so-called "modRNA" (modified RNA), which has a completely different effect in the body and inevitably entails hitherto unnoticed risks.

1. Decrease in live births as a vaccination side effect? deStatis database

A significant decline in live births was observed in Europe and worldwide at the beginning of 2022. In particular, the decline in live births also started in Germany exactly 9 months after the start of the vaccination campaign, with the authors concluding: "However, vaccination and birth statistics are considered accurate, at least within a margin of error of 10%. Therefore, the presented coincidence between vaccination and the nine-month delayed abrupt decline in live birth rate can be considered statistically certain. "¹ Accurate correlations in this sense can also be derived in Switzerland, even depending on the vaccination rate of the canton. We reported on this here.

1.1 Correlation or causality?

In Figure 2, the relationships of different influencing factors known so far are shown in a cause-effect diagram. That the injections are the main cause of the abrupt decline in live births cannot be deduced with certainty at the present time. It must be assumed that there are other unknown factors, which have not been recorded in Figure 2. Relevant information on social and psychological stress caused by family, occupational, or governmental interventions, such as cordoning off, wearing masks, Covid-19 testing, social distancing, and "forced vaccination," is missing from the databases. Nevertheless, the authors conclude, "Although each of the listed factors may contribute to varying degrees to family planning and natural conception statistics, none of them is per se able to explain the abrupt, remarkable, and unique decline in live births as of January 2022 in all European countries studied. "¹

Even though it must be assumed that women play a dominant role with regard to changes in the number of live births, the role of men must not be neglected under any circumstances!

"...coincidence between the vaccine uptake and the nine months-lagged abrupt drop of the live births rate can be considered statistically sound."

The authors of a study by the German Federal Institute for Population Research, which looked at the circumstance of the reduced number of live births, concluded that uncertainty and fear of future economic development was the most likely reason for parents' decision to postpone their desire to have children.² Bergholz & Steger rightly noted that no evidence was provided for this claim. In contrast, a more family-oriented living situation during the period of closures and home office, known as the cocooning effect, may even have exerted a positive influence on parents' decision to have children^.1

2. Vaccine adverse effects in the male reproductive tract: indirect evidence of male infertility from the UK Yellow Card database.

The incidence of reported adverse events affecting the reproductive tract is approximately 100-fold lower in males than in females. However, each of the reported adverse events must be expected to have a significant impact on male fertility. The three most commonly documented vaccine side effects include, in descending order, erectile dysfunction, testicular pain, and scrotal pain, with the absolute frequency of occurrence of the various vaccine side effects for the most commonly administered BioNTech injection illustrated in the figure below.

It is surprising that in relation to the 1 million doses administered, significantly more fertility-related vaccination adverse events were listed for the manufacturer Moderna. Possibly, this circumstance is due to the significantly increased proportion of contained mRNA in the injection of Moderna (mRNA-1273, 100µg RNA/dose) compared to BioNTech/Pfizer (BNT162b2, 30µg RNA/dose)?

2.1 Close correlation between the vaccination side effect heart failure and the occurrence of erectile dysfunction: one cause - two effects?

Of particular interest is the fact that a close correlation between the incidence of heart failure and the incidence of erectile dysfunction can be derived for all three manufacturers investigated (BioNTech, Moderna, AstraZeneca) in the UK reporting system. On closer examination, the authors' conclusion appears conclusive that this relationship is derived from the shared pathophysiological basis of Erectile Dysfunction and heart failure. The underlying and known mechanism, namely the endothelial dysfunction of the small capillaries in connection with blood clots, could explain the close connection of the frequency of occurrence of both disease patterns.

In this context, it is also interesting to note that erectile dysfunction occurs more frequently than heart failure for Moderna injections, which is not the case with the other manufacturers. Possibly the significantly increased proportion of mRNA contained in the product also plays a role here, or the fact that other lipid nanoparticles were used?

In summary, the authors conclude that, against the background of available data, it is completely incomprehensible that preclinical animal studies only scratch the surface when it comes to a valid analysis of the possibility of fertility-related side effects. We already reported on the background of the (not) performed "exclusion studies" of reproductive toxicity, as well as the data on the biodistribution of the toxic lipid nanoparticles, which clearly emerges from the preclinical documentation as well as the Pfizer post-marketing studies, both with regard to men and women.

3. Vaccination side effect reduced sperm quality after Covid injection?

Several studies investigating sperm quality - mainly in sperm donors - have been published to date. Only a small number of studies investigated progressive sperm motility. Overall, the authors conclude that the quality and robustness of the available studies on sperm quality effects are of moderate to poor quality. Among other things, there is a lack of control groups and only one study³ - which was also the only one to observe a decrease in sperm count - an adequate observation period of more than three months was chosen. A decrease in sperm concentration by -15.4% and decrease in total motile sperm count by -22.1% could be observed, but "boosted" subjects were not included for unexplained reasons.

"In summary, the authors conclude that in light of available data, it is completely incomprehensible that preclinical animal studies only scratch the surface when it comes to a valid analysis of the possibility of fertility-related side effects."

However, upon personal inquiry by Bergholz & Steger¹ it was learned that "the booster represents an additional intervention that could affect the final result and was therefore excluded in order to obtain a clean methodology." As with the German Federal Institute for Population Research study mentioned earlier,² in the only study that observed a reduction in sperm quality as a result of Covid injections, the authors come to an unsupportable conclusion without a tenable data basis: "Since the vaccines contain mRNA and not live virus, it is unlikely that the vaccine affects sperm parameters." It should be noted that the relevant component of RNA-based injections is not the mRNA of the virus, but the modRNA delivered by lipid nanoparticles, which will be discussed later in the article.

A review of the studies on sperm quality impairment already published and also analyzed by Bergholz & Steger can also be found in our article on vaccination side effects on male fertility.

4. Inheritance of injected modRNA by gene integration into male germ cells?

A comprehensive excursus on the possibility of rewriting (viral) RNA into DNA clearly shows that this can be done in the presence of s.g. reverse transcriptase (integration of viral RNA makes up about 8% of the human genome).⁴ is possible. However, much more significant is the fact that RNA can be written back into DNA even without the presence of reverse transcriptase. The presence of so-called LINE-1 elements, which acts as an endogenous (i.e., cell-internal) reverse transcriptase and accounts for about 17% of the human genome,⁵ enables the integration of RNA into DNA. These facts, as well as the fact that this pathway could be demonstrated for the reverse transcription of viral SARS-CoV-2 RNA as well as "inoculated" mRNA, are still skillfully ignored in public reporting^.1

"The circumstance of possible inheritance of the genetic information for endogenous production of the spike proteins becomes particularly important against the background that the injected RNA is not simple mRNA but so-called modRNA."

"If it turns out that vaccine-derived RNA that is rewritten into DNA can indeed be integrated into the genome of a germ cell, there is also a high probability of inheritance and production of spike proteins in the offspring. High levels of LINE1 have been found in sperm that transcribe exogenous RNA into DNA and plasmids that can package this DNA and deliver it to the egg after fertilization. As a result, the plasmids proliferate in the embryo. "¹

The fact that the administered RNA is also transported to the testes, from which a potential integration of the RNA into the male germ cells can be deduced, both from internal studies of the company Pfizer, as well as from existing publications on the properties of the lipid nanoparticles, about which we also already reported. The fact that the genetic information for the body's own production of the spike proteins may be inherited is particularly important in view of the fact that the injected RNA is not simply mRNA but so-called modRNA.

4.1 What is modRNA and to what extent is it relevant for assessing current and long-term fertility-impairing vaccine damage?

The active agent of RNA-based injections is not simply an mRNA molecule carrying the information to synthesize a viral protein, but a modRNA specifically designed for translational efficacy and longevity, encapsulated in LNPs to bypass biological barriers and gain access to all cells, including the heart and brain - possibly including germ cells.

Since RNA is involved in regulating gene expression, cells have mechanisms to shut down unneeded mRNA species; however, these protective mechanisms do not work with modRNA, which also raises the question of if and when spike protein production stops at all in the bodies of injected subjects (70% of the world's population)?

The "seeded" RNA does not mimic viral RNA, but is "humanized" to promote ribosomal translation (reading of RNA information and synthesis of the viral spike protein within cells) by human cellular equipment. If it is confirmed that, as stated above, injected modRNA leads to integration into the genome of male germ cells (gametes), the consequence would be that the offspring of these males could also express the spike protein in their own bodies.

Conclusion

The authors conclude that the bottom line is that there are several conceivable ways in which spike proteins in reproductive organs can affect germ cell development and semen quality. To date, no one knows whether the reported deterioration in semen quality after Covid-19 injections is temporary or a permanent effect.

In a forceful appeal, Bergholz & Steger¹ call for science and medicine to free themselves from political narratives.

Medical science needs a reality check and must return to reason and evidence-based facts to restore its damaged credibility. In addition to higher subject/participant numbers and longer follow-up time, future studies should publish information on both vaccine types and batch numbers associated with the results obtained, as there is evidence of great variability between different batches, with a minority of batches causing the majority of severe adverse effects. Interdisciplinary discussion of potential adverse health effects must not only be allowed, but encouraged.

"Medical science needs a reality check and must return to reason and evidence-based facts to restore its damaged credibility."

In this particular situation, scientists and physicians need to recognize, in particular, that the active ingredient of "RNA-based vaccines" is not simply an mRNA molecule, as found millions of times in our cells, but a modRNA engineered for longevity that can enter any of our cells to produce a viral protein.

But what should be the advantage for an originally healthy cell of our heart or brain to start synthesizing a viral protein that transforms this cell from a "friend" to an "enemy" and consequently to be attacked by our immune system?